What Is the Function of Citicoline?
What is citicoline?
As a professional supplier of plant Extract Powder raw materials,Kintainutri® provides citicoline, which is a naturally occurring endogenous compound with the chemical name of cytidine-5'-diphosphate choline. Our Citicoline Powder has a purity of ≥ 98% (detected by HPLC), meeting the standards of the USP/EP/JP three major pharmacopoeias. This molecule is formed by the connection of choline and cytidine through a phosphodiester bond, and this unique structure gives it dual biological activities.
The Core Function of Citicoline
Citicoline exerts neuroprotective effects through multiple mechanisms:
(1) Promoting the repair of neural cell membranes: Clinical studies have shown that citicoline can significantly promote the synthesis of phosphatidylcholine. Animal experiments have revealed that a dose of 50mg/kg can increase the phospholipid content in the cerebral cortex by 28%.
(2) Improving brain energy metabolism: In brain hypoxia models, citicoline can increase ATP production by 39%, effectively maintaining the energy supply of neurons.
(3) Regulating neurotransmitter levels: Multiple studies have confirmed that citicoline particularly promotes the release of dopamine by 32% and acetylcholine by 41%, thereby improving cognitive function.
Citicoline has clear therapeutic effects in cerebrovascular diseases:
(1) Acute treatment: Intravenous injection of citicoline can reduce the volume of cerebral infarction by 45% (data from the rat model of middle cerebral artery occlusion).
(2) Rehabilitation during the recovery period: Clinical phase III trials have shown that oral citicoline preparations can significantly improve the NIHSS neurological function score of patients by 2.7 points.
Citicoline demonstrates unique value in the field of ophthalmology:
(1) Glaucoma treatment: Citicoline can effectively lower intraocular pressure by 7.2 mmHg, and the blood pressure-lowering effect can last for 6 hours.
(2) Improvement of dry eye syndrome: It can increase tear secretion by 41%, alleviating dry eye symptoms in the eyes.
(3) Retinal protection: Experimental results show that citicoline can reduce the apoptosis of photoreceptor cells by 63% and protect visual function.
Kintainutri® ensure the excellent quality of its citicoline
Raw material traceability management
Production process control
We employ advanced online process analysis technology (PAT) to conduct real-time monitoring of the key quality attributes (CQA) of the production process, ensuring that the process parameters of each batch of products comply with the predetermined standards.
Comprehensive final product testing
Kintainutri® conducts 23 rigorous tests on each batch of finished products to ensure they meet the highest quality standards.
Kintainutri® the preferred partner for global manufacturers
International Certification Assurance
Kintainutri® strictly adheres to international quality standards. We have obtained dual certifications of ISO9001 quality management system and ISO22000 food safety management system. Our quality team ensures that every production process complies with the certification requirements, thereby guaranteeing the stability and reliability of product quality.
Kintainutri® offers customers a comprehensive range of customized solutions:
We support customization of different packaging specifications ranging from 1kg sample bags to 25kg industrial containers.
Our technical team can adjust the product particle size according to customer requirements, providing special specifications within the D50 range of 10-100μm.
We also accept value-added services such as compound formula premixes to meet customers' specific needs.
Self-owned warehousing and logistics system
The warehouse of Kintainutri® implements a strict system of storing raw materials and finished products in separate areas.
We have a 24-hour uninterrupted temperature and humidity monitoring system in place.
We offer bonded warehouse stocking services to ensure the flexibility of the supply chain.
At present, our inventory is sufficient and customers can now place orders and enjoy fast delivery services.
Quick Response Mechanism
The professional service team of Kintainutri® makes the following commitments:
Our customer service staff guarantee that they can respond to customer inquiries promptly.
Kintainutri® logistics team will complete the formulation of the sample delivery plan within 24 hours.
Our warehousing team ensures that the outbound process for large order shipments is completed within 48 hours.
By choosing Kintainutri®, you not only get high-quality raw material products, but also a comprehensive strategic partner. We welcome you to contact the sales engineer team of Kintainutri® at any time to obtain the latest product information and competitive pricing plans.
📩For details of our manufacturing process or to obtain samples, please feel free to contact us!